New hope for blood vessels?

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Given the prevalence of diabetes, it’s not surprising that we have to consider replacing damaged blood vessels.

After all, Type 2 diabetes damages endothelial cells.  These cells have all sorts of problems in the presence of high blood sugar levels.  (This is also one of the reasons fingers and limbs need to be amputated, because of the tissue damage. )

Now, a new solution may be available from China.  [Dr. Xingyu Jiang, Southern University of Science and Technology, Shenzhen, China is the primary researcher, his compatriots at Southern University are  Shiyu Cheng, Chen Hang, Li Ding, Lei Mou, Jie Qi, and Ruihua Dong.) Drs. Lixue Tang and WEnfu Zheng are associated with the University of Chinese Academy of Sciences (Beijing).  Drs. Liujun Jia and Yan Zhang are from the Chinese Academy of Medical Sciences (Beijing).   They reported their results in Matter, “Electronic Blood Vessel”.]

Electronic Blood Vessel

Dr. Jiang prints a layer of liquid metal ink (primarily gallium and indium) atop a flexible, biodegradable polymeric membrane. (The liquid metal serves as an electrode.)  This structure is then rolled into a cylinder to create a 2 mm wide blood vessel.

Why do they need an electrode?  Because sending pulses to the electrode stimulates living endothelial cells to gather and proliferate on the structure- that makes it just like regular blood vessels, lined with endothelial cells. (Dr. Jiang feels these are less like to engender blood clots.)

(Electrical fields can also be used to make the vessel more permeable [in a process called electroporation], so it can deliver drugs to neighboring cells.)

One of the first places they are considering testing this new vessel is as a carotid artery replacement.

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12 thoughts on “New hope for blood vessels?”

  1. The marvels of tech indeed! Just yesterday as my son was working on his final projects for his final year of high school, we were discussing just the same – about all that tech has made possible for us.. And considering who he is, and that he will be off to college in fall to learn and do more of that, I know he will be building something like this as well soon enough..

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