Do you remember playing Mad Libs when you were a kid?
Continue reading It’s just a silly little love song. No. It’s a contest.
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It’s just a silly little love song. No. It’s a contest.
Monthly Archives: January 2020
Early Detection of Breast Cancer Recurrence
Friday the 13th. Yeah, I know, lots of people are superstitious.
But, not Dr. Bryan Schneider (of Indiana University, with Drs. M Raodvich, M Jiang, C Chitambar, R Nanda, C Falkson, FC Lynce, C Gallagher, C Isaacs, M. Blaya, E Paplomata, R Walling, K Daily, R Mahtani, M Thompson, R Graham, M Cooper, D Pavlick, L Albacker, J Gregg, C Bales, BA Hancock, E Cantor, F Shen, A Stomiolo, S Badve, T Ballinger, and K Miller). Nope. They presented their clinical trial results at the 2019 San Antonio Breast Cancer Symposium that day. Their paper, GS5-02, Detection of circulating tumor DNA (ctDNA) after neoadjuvant chemotherapy is significantly associated with disease recurrence in early-stage triple-negative breast cancer (TNBC): Preplanned correlative results from clinical trial BRE12-158 ? (I know, I know… That’s a mouthful. But here’s what it really is- a new detection technique for solid tumors- like those that obtain for breast cancer.)
Continue reading Early Detection of Breast Cancer Recurrence
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He would be 91
Today is actually Martin Luther King’s birthday. (No, it’s not next Monday. That’s just the convenient choice the government makes to provide a 3 day weekend. [That also coincides with the (racist) holiday that obtained in Virginia for more than a century- the Lee-Jackson day, theoretically celebrating the two Confederate generals, but really promoting the hagiography of the racist South.) Had King not been murdered (and, of course, were still alive), he would be 91 today.
Continue reading He would be 91
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MSC to the rescue?
We discussed late last year how the injection of stem cells seems to help heart patients recover. Not because the stem cells are growing and rebuilding the heart. No, they are helping because they are stimulating an immune response that helps the heart recover.
Continue reading MSC to the rescue?
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Again? Really?
Here we go again!
Another article in the Wall Street Journal that indicates it has stopped providing analysis and depth in news reporting. And, you can bet that a bunch of other papers will use the same basic facts that will mislead you. (Since I wrote that sentence, it has come true- I’ve added the “pack’s” comments below.)
Continue reading Again? Really?
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Trial Phases
I was thinking about the post I wrote (about four hours ago- it won’t appear for a few weeks) and realized that the nuances of what I was saying may be lost on you. You don’t run- or even follow- clinical trials.
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A new protein yields resistance
Oh, no, Roy. Another article about antibiotic resistance?
Continue reading A new protein yields resistance
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The Dirty Secret About Antibiotic Resistance
We read almost every single week that a new drug has been developed to treat a chronic condition. And, the price tag for this pharmaceutical miracle is $ 400K, $ 1KK, or even $ 2KK. That’s the pot at the end of the rainbow that all of our pharmaceutical houses are seeking.
Continue reading The Dirty Secret About Antibiotic Resistance
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Fasting for a better BMI?
I have often written about diets and fads. No, I am not talking about keeping kosher, or the choices of vegetarian, vegan, or even pescatarian cuisine. Generally, the best diets are the Mediterranean diet (here’s one such mention) and for those at risk of kidney failure, diabetes, even epilepsy, or traumatic brain injury, the keto diet.
Continue reading Fasting for a better BMI?
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Let’s get MRSA!
Here’s a new wrinkle. Our antibiotics are compounds that interfere with bacterial cell wall production, membrane integrity, protein biosynthesis, and DNA synthesis. But, given our overuse (and incomplete drug regimens), the microbes we hope to kill have already developed resistance to the antibiotics in our arsenal.
Continue reading Let’s get MRSA!
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